Barbara A. Horwitz
280A Briggs Hall
530.752.0169
bahorwitz (at) ucdavis (dot) edu
B.S., Zoology, University of Florida, 1961
M.S., Zoology, University of Florida, 1962
Ph.D., Physiology, Emory University, 1966
Cellular and metabolic physiology
Neural, hormonal, and genetic regulation of cellular oxidative metabolism, energy balance, obesity, and thermogenesis; intracellular signal transduction, role of cytosolic pH in effecting/modulating uncoupling of mitochondria, and role of ion movements in thermogenic events; effects of aging, nutritional, and environmental factors on brown fat thermogenesis; mechanisms underlying altered homeostasis during aging.
De Fanti BA, JS Hamilton, & BA Horwitz. Meal-induced changes in extracellular 5-HT in medial hypothalamus of lean (Fa/Fa) and obese (fa/fa) Zucker rats. Brain Res., 902: 164-170, 2001.
Warren, LE, TM Hoban-Higgins, BA Horwitz, JS Hamilton, & CA Fuller. Effects of 2G exposure on lean and genetically obese Zucker rats. J. Gravitational Physiol., in press.
Horwitz, BA, AM Gabaldón, & RB McDonald. Thermoregulation during aging. In: Functional Neurobiology, eds. Hof, PR & CV Mobbs. Academic Press: San Diego, pp. 839-854, 2001.
Jekabsons, MB & BA Horwitz. Nucleotide effects on liver and muscle mitochondrial non-phosphorylating respiration and membrane potential. Biochim. Biophys. Acta, 1503: 314-328, 2001.
Warren, LE, BA Horwitz, JS Hamilton, & CA Fuller. Effects of 2G on adiposity, leptin, lipoprotein lipase and uncoupling protein-1 in lean and obese Zucker rats. J. Appl. Physiol., 90:606-614, 2001.
De Fanti BA, DA Gavel, JS Hamilton, & BA Horwitz. Extracellular hypothalamic serotonin levels after dorsal raphe nuclei stimulation of lean (Fa/Fa) and obese (fa/fa) Zucker rats. Brain Res. 869: 6-14, 2000.
Gades MD, H Van Goor, GA Kaysen, PR Johnson, BA Horwitz, & JS Stern. Brief periods of hyperphagia cause renal injury in the obese Zucker rat. Kid. Int. 56: 1779-87, 1999.
McDonald, RB, BA Horwitz. Brown adipose tissue thermogensis during aging and senescence. In : J. Bioenergetics and Biomembranes. 31: 507-516, 1999.
McDonald RB, TM Hoban-Higgans, RC Ruhe, CA Fuller, BA Horwitz. Alterations in endogenous circadian rhythm of core temperature in senescent Fischer 344 rats. Am. J. Physiol. 276: R824-R830, 1999.
Blanton C, BA Horwitz, RB McDonald. Neurochemical alterations during age-related anorexia. Proc. Soc. Expt. Biol. and Med. 221:153-165, 1999.
Jekabsons, MB, FM Gregoire, NA Schonfeld-Warden, CH Warden, BA Horwitz. T3 stimulates resting metabolism and UCP2 and 3 mRNAs but not non-phosphorylating mitochondrial respiration in mice. Am. J. Physiol. 277:E380-389, 1999.
Blanton, CA, BA Horwitz, C Murtagh-Mark, DW Gietzen, SM Griffey, RB McDonald. Meal patterns associated with the age-related decline in food intake in the Fischer 344 rat. Am. J. Physiol. 275: R1494-1502, 1998.
De Fanti, BA, RC Backus, JS Hamilton, DW Gietzen, BA Horwitz. Lean (Fa/Fa) but not obese (fa/fa) Zucker rats release cholecystokinin in their PVN after a gavaged meal. Am. J. Physiol. 275: E1-5, 1998.
Horwitz, BA, JS Hamilton, VH Routh, K Green, P Havel, A Chan. Adiposity and serum leptin increase in fatty (fa/fa) BNZ neonates without decreased VMH serotonergic activity. Am. J. Physiol. 274: E1009-E1017, 1998.
Gabaldon, AM, RB McDonald, BA Horwitz. Effects of age, gender, and senescence on beta-adrenergic responses of isolated F344 rat brown adipocytes in vitro. Am. J. Physiol. 274: E726-E736, 1998.
Oberbauer, AM, JS Stern, PR Johnson, BA Horwitz, JB German, SD Phinney, DH Beermann, D Pomp, JD Murray. Body composition of inactivated growth hormone (oMT1a-pGH) transgenic mice: generation of an obese phenotype. Growth, Develop., Aging. 61: 169-179, 1998.
Florez-Duquet, M, BA Horwitz, RB McDonald. Cellular proliferation and uncoupling protein content in brown adipose tissue of cold-exposed aging Fischer 344 rats. Am. J. Physiol. 274:R196-R203, 1998.
Johnson, PR, JS Stern, BA Horwitz, RE Harris, Jr, SF Greene. Longevity in obese and lean male and female rats of the Zucker strain: prevention of hyperphagia. Am. J. Clin. Nutr., 66: 890-903, 1997.
Horrigan, DA, BA Horwitz, JM Horowitz. Serotonergic modulation of hippocampal pyramidal cells in euthermic, cold-acclimated and hibernating hamsters. Am. J. Physiol.: 273 (Regulatory, Integrative and Comparative Physiol.) R1291-R1298, 1997.
Routh, VH, JS Stern and BA Horwitz. Physiological Responses of Mammals to Overnutrition. Handbook of Physiology, Section 4: Environmental Physiology, vol. 2, eds., M. Fregly and C. Blatteis; Oxford Univ. Press, p. 1411-1435, 1996.
Horwitz, BA. Homeostatic responses to acute cold exposure: thermogenic responses in birds and mammals. Handbook of Physiology: Section 4: Environmental Physiology, vol. 1, eds., M. Fregly and C. Blatteis; Oxford Univ. Press, p. 359-377, 1996.
Specter, SE, JS Stern, BA Horwitz. Hypothalamic monoaminergic activity in obese Zucker rats in response to acute and chronic dietary stimuli. Am. J. Physiol., 270: E677-688, 1996.
McDonald, RB, M Florez-Duquet, C Murtagh-Mark, BA Horwitz. Relationship between cold-induced thermoregulation and spontaneous rapid body weight loss of aging F344 rats. Am. J. Physiol. 271:R1115-1122, 1996.
Specter, SE, BA Horwitz, JL Beverly. Basal and glucoprivic-induced changes in extracellular GABA in the ventral hypothalamus of Zucker rats. Am. J. Physiol., 271:R388-392, 1996.
Sztalryd, CJ, J Hamilton, BA Horwitz, P Johnson, FB Kraemer. Alterations of lipolysis and lipoprotein lipase in chronically nicotine-treated rats. Am. J. Physiol. 270:E215-223, 1996.