NPB Neurobiology, Physiology & Behavior |
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| Pamela A. Pappone |
| Professor 1107B Life Sciences 530.752.2673 papappone (at) ucdavis (dot) edu |
| Degrees: B.A., Biology, Reed College, 1972 Ph.D., Physiology and Biophysics, University of Washington, 1979 |
| Teaching Interests: Cell physiology |
| Research Interests: Role of membrane ion channels in the hormonal, metabolic, and developmental responses of fat cells. Pharmacology of membrane ion channels. Structure-function relations in nicotinic acetylcholine receptor channel proteins. |
| Selected Publications: Mauro, T., D.B. Dixon, L. Komuves, K. Hanley and P.A. Pappone. 1997. Keratinocyte K+ channels mediate Ca2+-induced differentiation. Journal of Investigative Dermatology 108:864-870. Ortiz-Miranda, S., J.A. Lasalde, P.A. Pappone and M.G. McNamee. 1997. Mutations in the M4 domain of the Torpedo californica nicotinic acetylcholine receptor alter channel opening and closing. Journal of Membrane Biology 158:17-30. Lee, S.C. and P.A. Pappone. 1997. Membrane responses to extracellular ATP in isolated rat white adipocytes. Pflugers Archiv. 434:422-428. Lee, S.C. and P.A. Pappone. 1997. Effects of P2 purinergic receptor stimulation in brown adipocytes. American Journal of Physiology. 273:C679-C686. Pappone P.A. and S.C. Lee. 1996. Purinergic receptor stimulation increases membrane trafficking in brown adipocytes. J. Gen. Physiol. 108:393-404. Mauro, T., D.B. Dixon, K. Hanley, R.R. Isseroff and P.A. Pappone. 1995. Miloride blocks a keratinocyte nonspecific cation channel and inhibits Ca++-induced keratinocyte differentiation. Journal of Investigative Dermatology 105(2):203-208. Lee, S.C. and P.A. Pappone. 1995. Alpha-adrenergic stimulation activates a calcium-sensitive chloride current in brown fat cells. J. Gen. Physiol. 106:231-258. Lee, Y.-H., L. Li, J. Lasalde, L. Rojas, M. McNamee, S.I. Ortiz-Miranda and P.A. Pappone. 1994. Mutations in the M4 domain of Torpedo californica acetylcholine receptor dramatically alter ion channel function. Biophysical Journal 66:646-653. Lee, S.C., J.S. Hamilton, T. Trammell, B.A. Horwitz and P.A. Pappone. 1994. Adrenergic modulation of intracellular pH in isolated brown fat cells from hamster and rat. American Journal of Physiology, Cell Physiology 267:C349-C356. Lee, S.C., R. Nuccitelli and P.A. Pappone. 1993. Adrenergically activated calcium increases in brown fat cells: effects of Ca2+, K+, and K-channel block. American Journal of Physiology, Cell Physiology 264:C217-C228. Mauro, T.M., R.R. Isseroff, R. Lasarow and P.A. Pappone. 1993. Ion channels are linked to differentiation in keratinocytes. Journal of Membrane Biology 132:201-209. Pappone, P.A. and S. Ortiz-Miranda. 1993. Blockers of voltage-gated K channels inhibit the proliferation of brown fat cells in culture. American Journal of Physiology, Cell Physiology 264:C1014-C1019. |
| Affiliation: Center for Neuroscience |